2024 Tus sau: Kevin Dyson | [email protected]. Kawg hloov kho: 2023-12-16 23:34
Dab tsi yog Statins?
Statins yog ib chav kawm ntawm cov tshuaj feem ntau muab los ntawm kws kho mob los pab txo qis cov roj cholesterol hauv cov ntshav. Los ntawm kev txo qis, lawv pab tiv thaiv kev mob plawv thiab mob stroke. Cov kev tshawb fawb pom tau tias, hauv qee tus neeg, statins txo qhov kev pheej hmoo ntawm plawv nres, mob stroke, thiab txawm tias tuag los ntawm kab mob plawv los ntawm 25% mus rau 35%. Cov kev tshawb fawb tseem qhia tau hais tias statins tuaj yeem txo qhov kev pheej hmoo ntawm kev mob stroke lossis plawv nres li ntawm 40%.
Leej twg yuav tsum noj statins?
Kev kwv yees yog tias ntxiv rau cov tib neeg twb tau noj lawm, lwm 15 lab txog 20 lab tus tib neeg yuav tsum tau noj tshuaj statin raws li lawv cov kev pheej hmoo rau mob plawv. Koj tus kws kho mob tuaj yeem kuaj ntshav yooj yim txhawm rau txiav txim siab cov roj cholesterol hauv koj cov ntshav. Yog tias koj muaj cov roj (cholesterol) siab LDL ("phem") cov roj (cholesterol) siab, koj yuav muaj feem ntau ntawm cov kab mob plawv, tshwj xeeb tshaj yog thaum muaj lwm yam uas ua rau koj muaj kev pheej hmoo. Koj cov roj (cholesterol) los ntawm ib qho twg.
Txawm li cas los xij, tsis yog txhua yam roj cholesterol phem. Nws yog qhov zoo, piv txwv li, kom muaj qib HDL ("zoo") cov roj cholesterol. HDL cholesterol tiv thaiv cov quav hniav hauv cov hlab ntsha los ntawm kev thauj cov roj (LDL) cov roj (cholesterol) phem tawm hauv cov ntshav mus rau lub siab. Los ntawm qhov ntawd, nws raug tshem tawm ntawm lub cev.
Yuav ua li cas statins ua haujlwm
tshuaj statin ua haujlwm los ntawm kev thaiv qhov kev ua ntawm lub siab enzyme uas yog lub luag haujlwm tsim cov roj cholesterol. Cov roj (cholesterol) ntau dhau hauv cov ntshav tuaj yeem ua rau muaj cov plaque nyob rau ntawm phab ntsa ntawm cov hlab ntsha. Qhov kev tsim kho ntawd tuaj yeem ua rau cov hlab ntsha nqaim lossis tawv. Cov ntshav txhaws tam sim ntawd hauv cov hlab ntsha uas nqaim tuaj yeem ua rau lub plawv nres lossis mob stroke.
Statins txo qis LDL roj cholesterol thiab tag nrho cov roj cholesterol. Tib lub sijhawm, lawv txo qis triglycerides thiab nce qib HDL cholesterol. Statins kuj tseem tuaj yeem pab txhim kho cov plaques hauv cov hlab ntsha, ua rau lub plawv tsis zoo.
Txoj kev ua neej nyob zoo thaum noj statin tuaj yeem txhim kho cov txiaj ntsig ntawm cov tshuaj. Nco ntsoov:
- noj zaub mov kom zoo, lub plawv zoo
- Ua kom lub cev tsis tu ncua
- txwv tsis pub haus cawv
- Tsis txhob haus luam yeeb
statin phiv cuam tshuam
Cov neeg feem coob uas siv tshuaj statin zam tau zoo heev. Tab sis qee tus neeg muaj kev phiv.
Cov kev mob tshwm sim feem ntau statin suav nrog:
- Headache
- nyuaj pw
- mob plab, mob plab, lossis qaug zog (myalgia)
- Kev nyuaj siab
- kiv taub hau
- Ntaus lossis ntuav
- mob plab los yog mob
- plab lossis roj
- Zoo plab
- Kev cem quav
- Raws
- qis ntshav platelets
Cov kev mob tshwm sim tsawg dua koj tuaj yeem muaj nrog statins yog:
- Nausea
- Hair loss
- Pins thiab koob xav, xws li pricking, loog, lossis tingling ntawm koj daim tawv nqaij
- mob siab, uas tuaj yeem ua rau koj xav tias koj mob khaub thuas
- mob pancreas, uas tuaj yeem ua rau mob plab
- teeb meem ntawm daim tawv nqaij xws li pob khaus lossis pob txuv
- teeb meem kev sib deev, xws li erectile kawg lossis kev sib deev tsis zoo
Statins tseem muaj cov lus ceeb toom tias tsis nco qab, tsis meej pem hauv lub hlwb, neuropathy, ntshav qab zib siab, thiab ntshav qab zib hom 2 tuaj yeem tshwm sim. Nws tseem ceeb heev kom nco ntsoov tias statins kuj tseem cuam tshuam nrog lwm cov tshuaj uas koj noj.
Cov Kev Mob Loj Loj ntawm Statins
Statins txuas rau qee qhov tsis tshua muaj tab sis muaj feem cuam tshuam loj, suav nrog:
- Myositis,uas yog o ntawm cov leeg. Qhov kev pheej hmoo ntawm kev raug mob ntawm cov leeg yuav nce ntxiv thaum qee cov tshuaj noj nrog statins. Piv txwv li, yog tias koj noj ib qho kev sib xyaw ntawm cov tshuaj statin thiab fibrate - lwm cov tshuaj txo cov roj cholesterol - qhov kev pheej hmoo ntawm cov nqaij ntshiv nce siab heev piv rau ib tus neeg uas siv statin ib leeg.
- nce qib ntawm CPK, lossis creatine kinase, cov leeg nqaij enzyme uas thaum nce siab, tuaj yeem ua rau mob nqaij, mob me, thiab cov leeg tsis muaj zog. Cov mob no, txawm tias tsis tshua muaj, tuaj yeem siv sijhawm ntev los daws.
- Rhabdomyolysis, mob nqaij tawv heev thiab puas. Nrog rau qhov mob no, cov leeg nqaij thoob plaws lub cev ua rau mob thiab tsis muaj zog. Cov nqaij ntshiv loj heev tso cov protein rau hauv cov ntshav uas sau rau hauv lub raum. Lub raum tuaj yeem ua puas tau sim tshem tawm ntau cov leeg nqaij los ntawm kev siv statin. Qhov no tuaj yeem ua rau lub raum tsis ua haujlwm lossis tuag taus. Hmoov zoo, rhabdomyolysis yog qhov tsawg heev. Nws tshwm sim tsawg dua ib ntawm 10,000 tus neeg noj statins.
Yog tias koj muaj ib qho kev piav qhia tsis tau piav qhia los yog mob leeg, rhiab, lossis qaug zog thaum noj statins, koj yuav tsum hu rau koj tus kws kho mob tam sim.
Qee qhov kev tshawb fawb txuas statin siv nrog kev yug me nyuam. Cov kws kho mob qhia cov poj niam cev xeeb tub kom tsis txhob siv cov tshuaj no.
Statin Side Effects Risk Factors
Qee yam tuaj yeem ua rau koj muaj kev pheej hmoo ntawm kev mob tshwm sim nrog statins. Tej zaum koj yuav muaj feem cuam tshuam yog tias koj:
- Noj ntau dua ib yam tshuaj los tswj koj cov roj cholesterol
- Yog poj niam
- Muaj lub cev me me
- Muaj 80 lossis siab dua
- muaj raum lossis kab mob siab
- Cia cawv ntau
- Muaj qee yam kev mob nkeeg, xws li hypothyroidism lossis neuromuscular ntshawv siab
Tshuaj statin thiab khoom noj sib cuam tshuam
Qee yam khoom noj thiab tshuaj tsis sib tov zoo nrog statins thiab tuaj yeem ua rau muaj kev phiv tsis zoo:
- kua txiv kab ntxwv, uas muaj cov tshuaj uas tuaj yeem hloov txoj hauv kev koj lub cev zom cov statins
- Ib tshuaj rau lub plawv dhia tsis xwm yeem hu ua amiodarone (Cordarone, Pacerone)
- Gemfibrozil (Lopid), tshuaj cholesterol
- Protease inhibitors, hom tshuaj HIV uas suav nrog saquinavir (Invirase) thiab ritonavir (Norvir)
- Qee cov tshuaj tua kab mob thiab tshuaj tua kab mob, xws li clarithromycin thiab itraconazole
- Qee cov tshuaj, xws li cyclosporine, uas txo koj lub cev tiv thaiv kab mob
Muaj lwm yam tshuaj uas tuaj yeem ua teeb meem yog tias koj noj cov tshuaj statins. Koj yuav tsum qhia koj tus kws kho mob txog tag nrho cov khw muag khoom lossis tshuaj noj, tshuaj ntsuab tshuaj, lossis cov vitamins uas koj siv.
Tau txais kev pab los ntawm Statin Side Effects
Koj tus kws kho mob tuaj yeem qhia qee txoj hauv kev los txo cov kev mob tshwm sim uas koj muaj nrog statins. Cov kev hloov no yuav pab tau, tab sis nrog koj tus kws kho mob tham ua ntej:
- So kom txaus los ntawm statins, uas tuaj yeem pab koj paub yog tias cov tshuaj ua rau mob nqaij lossis lwm yam kev mob tshwm sim
- Sim lwm yam tshuaj statin lossis koob tshuaj
- Hloov koj lub sijhawm ua haujlwm maj mam thiab hla kev tawm dag zog hnyav yog tias koj tsis siv rau lawv
- Sim lwm hom tshuaj kom txo koj cov roj cholesterol
- Noj cov tshuaj coenzyme Q10, uas tuaj yeem tiv thaiv kev mob tshwm sim hauv qee tus neeg
FDA-pom zoo statins
Cov tshuaj statin uas tau tso cai siv hauv Tebchaws Meskas suav nrog:
- Lipitor
- Livalo
- Mevacor lossis Altocor
- Zocor
- Pravachol
- Lescol
- YCrestor
Txij li thaum lawv tuaj txog ntawm kev ua lag luam, statins tau yog cov tshuaj kws tshaj lij hauv Tebchaws Meskas, nrog txog 17 lab tus neeg siv.
Pom zoo:
Kev Nyab Xeeb Kev Nyab Xeeb: Cov teebmeem tshwm sim, pov tseg tom qab tas sijhawm, thiab ntau dua
Koj puas noj tshuaj ntev ntev los tswj kev noj qab haus huv? Lossis koj puas tsuas ncav cuag cov tshuaj tom khw muag khoom ib ntus? Txawm li cas los xij, muaj ntau yam koj tuaj yeem ua kom paub tseeb tias koj tau txais txiaj ntsig zoo tshaj plaws los ntawm cov tshuaj - thiab nyob nyab xeeb hauv cov txheej txheem.
Hoodia Cov teebmeem tshwm sim, siv, thov, thiab ntau dua
Nws tau siv ntau xyoo rau cov neeg Amelikas rog rog kom pom dab tsi cov neeg South African hav txwv yeem paub innately - lossis yog li zaj dab neeg mus. Rau eons, cov neeg hav zoov tau nibbled ib hom succulent nroj tsuag hu ua Hoodia gordonii - thiab nyob twj ywm slim.
Tshuaj tiv thaiv kab mob shingles rau cov neeg laus: Cov teebmeem tshwm sim, Thaum twg txhaj tshuaj, thiab ntau ntxiv
Shingles tuaj yeem ua haujlwm txhua hnub - txij li hnav khaub ncaws mus rau hauv txaj - ib qho kev mob siab. Tus neeg ua txhaum tom qab qhov mob pob khaus no, uas tshwj xeeb tshaj yog nyob rau hauv cov neeg laus, yog tib tus kab mob uas ua rau muaj lwm yam tab sis mob hnyav:
Norepinephrine thiab Dopamine Reuptake Inhibitors (NDRIs): Cov teebmeem tshwm sim, kev cuam tshuam, thiab ntau ntxiv
Norepinephrine thiab dopamine reuptake inhibitors (NDRIs) yog cov tshuaj kho kev nyuaj siab. Lawv yog cov tshiab dua li thawj tiam antidepressants. Cov tshuaj tiv thaiv kev nyuaj siab sib txawv ua haujlwm sib txawv me ntsis. Ib qho txiaj ntsig nrog NDRIs yog tias lawv feem ntau tsis ua rau muaj kev mob tshwm sim uas tuaj yeem tshwm sim rau cov tshuaj tua kab mob.
Common Lurasidone (Latuda) Cov teebmeem tshwm sim: me me, hnyav, thiab ntau dua
Yog tias koj muaj tus mob schizophrenia lossis kev puas siab puas ntsws bipolar, tshwj xeeb tshaj yog kev nyuaj siab, koj tus kws kho mob yuav sau tshuaj rau koj ib hnub hu ua lurasidone (Latuda). Nws yog atypical lossis thib ob tiam antipsychotic (SGA).